Anti - Diarrheals

The treatment protocol to be followed in Diarrhea should be in the following order

  1. Rehydration: Give the patient plenty of orals fluids or ORS or start IV fluids if required.
  2. Probiotics: Ask the patient to consume Curd or Yogurt or Isabgol. Sporolac sachets or tablets (Lactobacillus) or Econorm sachets (S.Boulardii)can be given to restore bacterial flora in intestines.
  3. Antissecretory agents: Drugs like Racecodotril can be given to reduce the fluid loss.
  4. Antimotility agents: Drugs like Loperamide (Tab.Eldoper 2mg) or Diphenoxylate (Tab Lomotil) can be given to stop the gut movements.

Dietary Advice in Diarrhea

Advice plenty of water, Liquids, Black tea, Ganji, Buttermilk, Coconut water, Fruit juices, Biscuits, Overripe Bananas.

As loose motions decrease, Soft diet like Idli, Soft rice (Curd rice/Ghee rice),Rice with buttermiilk, Ganji, Fruits,etc.

Avoid heavy, hard, cold, hot, spicy and oily foods. 
Most commonly used Anti - Diarrheals are :

1. Loperamide 2mg

How Loperamide works

*Loperamide is an anti-diarrhoeal medication. It works by slowing down the contraction of the intestines thereby decreasing the speed at which the contents pass through it. This allows more time for reabsorption of fluids and nutrients, making the stools more solid and less frequent.

*It should not be used in patients with dysentery (diarrhea with blood)

*Do not use Loperamide if you have blood in your stool or if you are severely constipated.

*Use caution while driving or doing anything that requires concentration as Loperamide can cause dizziness and sleepiness.

Tab Eldoper 2mg STAT and 1 tab SOS
Tab Andial 2mg 
Tab Lopamide 2mg

2. Racecadotril 100mg in Adults
                            10mg in Paediatrics

Racecadotril is used in the treatment of diahrroea. It is used, when fluid and dietary measures are not sufficiently effective to control diarrhoea.

How Racecadotril works

Racecadotril has an anti-secretory effect. It reduces the secretion of water and electrolytes from the intestine. This helps to reduce the amount of fluid loss from the body in diarrhoea.

1.Racecadotril should be used together with an oral rehydration solution (ORS) to provide adequate fluid and electrolyte replacement.

2.Don't use Racecadotril, if you have blood and pus in the stools or fever. This may be due to bacterial infection and may need different treatment.

3.Not recommended to be taken more than 7 days.

4.Don't use Racecadotril, if you have uncontrolled vomiting.
    
Tab Zedott 100mg 1-1-1 
or 
Tab Racedot 100mg 1-1-1
or 
Tab Redotil 100mg 1-1-1
Zedott Baby Sachets 10mg 
Tab Zedott DT 10mg


*How does Racecadotril differ from loperamide?
-Racecadotril does not affect motility as compared to Loperamide. It means less chance of developing rebound constipation.




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