Ornidazole
Ornidazole 1. Class: Nitroimidazole Antimicrobial 2. Mechanism of Action Ornidazole disrupts the DNA of anaerobic bacteria and protozoa by forming free radicals that damage DNA, leading to cell death. It effectively targets anaerobic infections and protozoal infections. 3. Uses - Anaerobic Bacterial Infections: Effective against pathogens such as Bacteroides species, Clostridium species, and Fusobacterium species. - Protozoal Infections: Treats Trichomonas vaginalis (trichomoniasis) and Giardia lamblia (giardiasis). - Gynecological Infections: Used in combination therapy for bacterial vaginosis and other gynecological infections. 4. Rationale for Use - Effective Against Anaerobes and Protozoa: Targets specific pathogens not covered by many other antibiotics. - Good Tissue Penetration: Effective in treating infections in vario...